DISCLAIMER — Not financial advice. Educational content only, not an offer or solicitation to buy or sell any security. Biotech and small/mid-cap stocks are highly speculative and volatile and can result in a partial or total loss of capital. Do your own research and consult a licensed advisor where appropriate. / Contenuti a solo scopo informativo e didattico, non costituiscono consulenza finanziaria né offerta o sollecitazione al pubblico risparmio ai sensi delle normative CONSOB e SEC. Le azioni biotech e le small/mid cap sono strumenti altamente speculativi e volatili e possono comportare la perdita parziale o totale del capitale investito. Si raccomanda di effettuare sempre le proprie ricerche e, se necessario, di rivolgersi a un consulente abilitato.

Merlintrader Trading Pub
Biotech catalyst news and analysis. FDA PDUFA tracker

Merlintrader Trading Pub
Biotech catalyst news and analysis. FDA PDUFA tracker
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Calendars
Biotech Catalyst Calendar February 2026: PDUFA, BLA & Clinical Results

Biotech Catalyst Calendar February 2026: PDUFA, BLA & Clinical Results
One-page view of the key February 2026 biotech catalysts: only one line per ticker, grouped by date. Fixed PDUFA and BLA events are listed first; the others are February-window guidance from company and Street sources.
MARKET REPORT – WEEK 15–19 DECEMBER 2025

The coming week looks like a genuine pivot week for global markets, with three macro catalysts in sequence that will reshape expectations on rates, growth and inflation. The backdrop is a rotation into small caps and cyclicals, supported by a Fed that has shifted into a less aggressive “pause” mode and by a potential divergence between central banks: the BoE is expected to cut (18 Dec), the ECB is likely to stay on hold, and US CPI (18 Dec) together with labour data will refine the timing of 2026 rate cuts.
Wall Street Weekly Report Dec 9–15

Economic Events: The Week Ahead
KEY CATALYST FACT Federal Reserve FOMC Meeting (Dec 17–18) – markets are currently pricing an approximate probability of a 25 bp rate cut to 3.50%–3.75%, which would be the third cut of 2025. This decision is likely to be the single most important event affecting equity valuations in the following week.
PDUFA dates december 2025

December 2025 is the densest FDA decision month of the year. In only 26 days the agency is expected to rule on fourteen key dossiers across oncology (Breyanzi), cardiology (Aficamten), ophthalmology (EYLEA HD, LYTENAVA), rare diseases (Narsoplimab, Mitapivat), endocrine disorders (Relacorilant), infectious diseases (Zoliflodacin) and more.
Weekly Market Analysis & Trading Outlook

The week of November 24-29 closed with continued volatility as investors digested stretched AI valuations, mixed macro signals, and elevated geopolitical tensions. Major indexes ended modestly lower: S&P 500 [finance:S&P 500] -1.9%, Nasdaq [finance:Nasdaq Composite] -2.7%, Dow [finance:Dow Jones Industrial Average] -1.9%.